Author

Karel Půbal

University of Chemistry and Technology, Prague

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:protein design· 1 Assay:protein sequence· 1 Approach:statistical model· 1

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Karolína LoužeckáiD· 1 shared Kseniia Kushnir· 1 shared Petra LipovováiD· 1 shared Vladimı́r SetničkaiD· 1 shared Vojtěch SpiwokiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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Karolína LoužeckáORCID

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1 paper

Recent·Most cited

Toward a Minimal Amino Acid Alphabet for Protein Design

Karel Půbal, Kseniia Kushnir, Vojtěch Spiwok, Karolína Loužecká, Vladimı́r Setnička, Petra Lipovová

The paper designs proteins using reduced amino acid alphabets and shows that 8 amino acids can form stable proteins, while smaller alphabets fail in experimental validation.

FEBS Journal · Sep 29, 2026Peer-reviewedBioinformatics