T-cell receptor structures and predictive models reveal comparable alpha and beta chain structural diversity despite differing genetic complexity
Nele P. Quast, Brennan Abanades, Bora Guloglu, Vijaykumar Karuppiah, Stephen J Harper, Matthew I. J. Raybould, Charlotte Mary Deane
The paper evaluates TCR structure prediction models using a large dataset, finds comparable structural diversity in alpha and beta chains, and provides over 1.5M predicted structures for further analysis.
Communications Biology · Mar 4, 2025Peer-reviewedImmunology