The Impact of Digital Histopathology Batch Effect on Deep Learning Model Accuracy and Bias
Frederick Matthew Howard, James M. Dolezal, Sara E. Kochanny, Jefree J. Schulte, Heather Chen, Lara Rosaline Heij, Dezheng Huo, Rita Nanda, Olufunmilayo Ibironke Olopade, Jakob Nikolas Kather, Nicole A. Cipriani, Robert L. Grossman, Alexander T. Pearson
This paper shows that digital histopathology batch effects in TCGA data affect DL model accuracy and bias, and proposes a method to address this issue.
Nature Communications · Jul 20, 2021Peer-reviewedBioinformatics