Heritable environments: bias due to conditioning on a collider in models with polygenic scores
Evelina Tamerlanov Akimova, Richard Breen, David M. Brazel, Melinda C Mills
This paper shows that controlling for heritable covariates in models with polygenic scores can introduce bias due to collider conditioning, leading to spurious associations.
bioRxiv · Nov 2, 2020 · PreprintGenetics