Beckwith-Wiedemann syndrome and large offspring syndrome involve alterations in methylome, transcriptome, and chromatin configuration.
Yahan Li, Ping Xiao, Frimpong Boadu, Anna K. Goldkamp, Snehal Nirgude, Jianlin Jack Cheng, Darren E. Hagen, Jennifer M. Kalish, Rocío Melissa Rivera
This study identifies molecular subgroups and epigenetic alterations in Beckwith-Wiedemann Syndrome and large offspring syndrome across methylome, transcriptome, and chromatin architecture.
medRxiv · Dec 14, 2023 · PreprintGenetic & Genomic Medicine