A Ratiometric Catalog of Protein Isoform Shifts in the Cardiac Fetal Gene Program
Yu Han, Shaonil Binti, Sara A. Wennersten, Boomathi Pandi, Dominic C. M. Ng, Edward Lau, Maggie P. Y. Lam
The paper identifies widespread isoform usage shifts in fetal and postnatal mouse hearts using proteome-wide ratio quantification, revealing novel isoform switches and evolutionary patterns.
JCI Insight · Aug 7, 2025Peer-reviewedBiochemistry