Systems BiologyGlycobiologyPeer-reviewed
Integrated tumour-immune cell response modelling of Luminal A breast cancer details malignant signalling and ST3Gal1 inhibitor induced reversal
Hikmet Emre Kaya, Kevin J. Naidoo
The paper develops a systems model of MUC1 glycosylation and immune interactions in Luminal A breast cancer, showing that sialyltransferase inhibition reverses cancerous signaling.
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