Exhaled breath condensate proteomics using amphipols improves protein detection but reveals statistical challenges in respiratory disease biomarker discovery
Eline Schillebeeckx, Andrea Argentini, Jo Raskin, Jan P. van Meerbeeck, Kris Gevaert, Kevin Lamote, Esperanza Fernández
This study uses amphipols to improve protein detection in exhaled breath condensate but finds high variability and missing data hinder reliable biomarker discovery.
bioRxiv · Nov 21, 2025 · PreprintPathology