Multi-Level Attention Graph Neural Network for Clinically Interpretable Pathway-Level Biomarkers Discovery
Xiaohan Xing, Fan Yang, Hang Li, Jun Zhang, Yu Zhao, Junzhou Huang, Max Q.‐H. Meng, Jianhua Yao
The paper introduces MLA-GNN, a graph neural network that discovers clinically interpretable pathway-level biomarkers by integrating multi-level graph features and a saliency mechanism, achieving state-of-the-art results on transcriptomic and proteomic data.
bioRxiv · Dec 3, 2020 · PreprintBioinformatics