TopoLa: A Universal Framework to Enhance Cell Representations for Single-cell and Spatial Omics through Topology-encoded Latent Hyperbolic Geometry
Kai Zheng, Shaokai Wang, Yunpei Xu…·Jianxin Wang
TopoLa enhances cell representations in single-cell and spatial omics by using topology-encoded latent hyperbolic geometry, improving performance across multiple tasks.