A genome wide search for non-additive allele effects identifies PSKH2 as involved in the variability of Factor V activity.
Blandine Gendre, Ángel Martínez-Pérez, Marcus Edi Kleber, Astrid van Hylckama Vlieg, Anne Boland, Robert Olaso, Marine Germain, Gaëlle Munsch, Angela P. Moissl, Pierre Suchon, Juan Carlos Souto, José Manuel Soria, CHARGE Hemostasis working group, Jean‐François Deleuze, Winfried März, , David‐Alexandre Trégouët
The paper identifies PSKH2 as a gene influencing variability in Factor V plasma activity through genome-wide analysis of non-additive allele effects.
bioRxiv · Feb 8, 2024 · PreprintGenetics