GeneticsbioRxivPreprint
Complement component 4 genes contribute sex-specific vulnerability in diverse illnesses
Nolan Kamitaki, Aswin Sekar, Robert E. Handsaker…·Steven A. McCarroll
This study identifies C4 genes in the MHC locus as sex-specific contributors to risk for lupus, Sjogrens syndrome, and schizophrenia, with stronger effects in men than women.