Cancer BiologybioRxivPreprint
Acute Myeloid Leukemia with deletion 5q is an epigenetically distinct subgroup defined by heterozygous loss of KDM3B
Katherine A. Kelly, Linda Welte, Etienne Sollier…·Christoph Plass
The paper identifies del(5q) AML as an epigenetically distinct subgroup driven by KDM3B haploinsufficiency, linked to DNA hypermethylation and H3K9me1/2 dysregulation.
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