Author

Hanne E.J. Meijers-Heijboer

Amsterdam NeuroscienceORCID 0000-0003-1169-3853Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:database / resource· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Approach:statistical model· 1

Frequent Co-Authors

Henne H. HolstegeiD· 2 shared Marc HulsmaniD· 2 shared Philip ScheltensiD· 2 shared Debbie Horsten· 1 shared Elizabeth Wemmenhove· 1 shared Frans W.A. van PoppeliD· 1 shared Iris E. JanseniD· 1 shared Karlijn Pieterse· 1 shared

Activity by Year

2018-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Henne H. HolstegeORCID

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2 papers

Recent·Most cited

NeuroscienceEuropean Journal of EpidemiologyPeer-reviewedOct 25, 2018

The 100-plus Study of Dutch cognitively healthy centenarians: rationale, design and cohort description

Henne H. Holstege, Nina Beker, Tjitske Dijkstra…·Philip Scheltens

The 100-plus Study characterizes Dutch centenarians with preserved cognitive health, finding associations between APOE alleles and mortality, and higher education and socio-economic status.

91 citationstop 3%

humandatabase / resource

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GeneticsEuropean Journal of Human GeneticsPeer-reviewedSep 26, 2018

Centenarian Controls Increase Variant Effect-sizes by an average two-fold in an Extreme Case-Extreme Control Analysis of Alzheimer’s Disease

Niccoló Tesi, Sven J. van der Lee, Marc Hulsman…·Henne H. Holstege

This study shows that using centenarians as extreme controls increases AD variant effect-sizes by two-fold, enabling replication in small samples.

65 citationstop 4%

humanGWAS summary statistics

𝕏 PostBluesky