Lan Wang

Protenix-v1 is an open-source biomolecular structure prediction model that outperforms AlphaFold3 with the same training data cutoff, offering improved accuracy and new features for real-world applications.

PXDesign achieves high hit rates for protein binder design by combining generative models and filtering strategies, validated experimentally and made publicly available.

An open AlphaFold3 reproduction, with weights, inference and training code, that matches AF3 on ligand and RNA benchmarks, beats AlphaFold-Multimer 2.3 on protein interfaces and flags possible memorisation.