Author

Tonglin Zhang

Purdue University West LafayetteORCID 0000-0003-3312-2293Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Assay:spatial transcriptomics· 3 Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Approach:graph neural network· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Baijian YangiD· 3 shared Jing SuiD· 3 shared Qianqian SongiD· 3 shared Ziyang TangiD· 3 shared Xiang LiuiD· 2 shared Zuotian LiiD· 2 shared Aishwarya BudhkariD· 1 shared Bo LiiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 31 mutual co-author links

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3 shared papersBioinformatics

Baijian YangORCID

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3 papers

Recent·Most cited

BioinformaticsNature CommunicationsPeer-reviewedAug 23, 2025

SpaIM: Single-cell Spatial Transcriptomics Imputation via Style Transfer

Bo Li, Ziyang Tang, Aishwarya Budhkar…·Qianqian Song

SpaIM improves spatial transcriptomics by imputing missing gene expressions using scRNA-seq data, outperforming 12 existing methods across 53 datasets.

26 citationstop 1%

spatial transcriptomicsscRNA-seq

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BioinformaticsNature CommunicationsPeer-reviewedSep 12, 2023

SiGra: Single-cell spatial elucidation through image-augmented graph transformer

Ziyang Tang, Zuotian Li, Tieying Hou…·Qianqian Song

SiGra integrates spatial images and transcriptomics data to enhance spatial domain detection and improve characterization of cellular heterogeneity and communication in tissues.

76 citationstop 2%

humanmouse

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BioinformaticsbioRxivPreprintAug 3, 2023

SpaRx: Elucidate single-cell spatial heterogeneity of drug responses for personalized treatment

Ziyang Tang, Xiang Liu, Zuotian Li…·Qianqian Song

SpaRx identifies spatial cellular heterogeneity in drug responses across tumor lesions and reveals mechanisms of drug resistance through a graph-based domain adaptation model.

2 citations

humanspatial transcriptomics

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