BioinformaticsbioRxivPreprint
Inverse signal importance in real exposome: How do biological systems dynamically prioritize multiple environmental signals?
Thoma Itoh, Yohei Kondo, Tomoya Nakayama…·Honda Naoki
The paper introduces a machine learning framework, ISI, to infer how organisms prioritize environmental signals from time-series data, applied to medaka fish gonadal development under natural conditions, revealing dynamic signal importance and gene expression correlations.
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