Author

Signe Hässler

InsermORCID 0000-0003-4263-3079Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1

Frequent Co-Authors

Adrien SixiD· 2 shared Alexandra Roux· 2 shared Alice CourtiesiD· 2 shared Caroline Aheng· 2 shared Claire Ribet· 2 shared David KlatzmanniD· 2 shared Encarnita Mariotti‐FerrandiziD· 2 shared Fabien PitoisetiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Adrien SixORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 27, 2026

A regulatory T cell signature provides a shared molecular basis for the therapeutic window of opportunity in rheumatic disease

Marie Binvignat, Federica Martina, Fabien Pitoiset…·Encarnita Mariotti‐Ferrandiz

The paper identifies a shared Treg dysfunction signature across rheumatic diseases, suggesting a therapeutic window of opportunity for Treg-targeted treatments.

DOI 10.64898/2026.09.21.753213

humanproteomics

𝕏 PostBluesky

ImmunologyArthritis & RheumatologyPeer-reviewedNov 14, 2025

Immunological Profiling in Knee Osteoarthritis: Treg Dysfunction as Key Driver of Pain

Marie Binvignat, Johanna Dubois, Maria Marco Salvador…·Jérémie Sellam

This study identifies Treg dysfunction as associated with OA-related pain through multi-omic analysis of peripheral blood from knee OA patients.

7 citationstop 5%

humanbulk RNA-seq

𝕏 PostBluesky