Author

Shavkatjon Qoshimboyev

New Uzbekistan UniversityORCID 0009-0002-0291-6912Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Jamoliddin RazzokoviD· 1 shared Mukhriddin MakhkamoviD· 1 shared Parthiban MarimuthuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBiophysics

Jamoliddin RazzokovORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintOct 9, 2026

A permeable G310 constriction limits K+ flux in the activated KCNQ2 pore and is disrupted by the encephalopathy variant G310S

Shavkatjon Qoshimboyev, Parthiban Marimuthu, Mukhriddin Makhkamov, Jamoliddin Razzokov

This study identifies G310 as the flux-limiting constriction in the activated KCNQ2 pore and shows the G310S variant reduces K+ conduction by altering the water column and ion movement.

DOI 10.64898/2026.10.05.756556

protein structurestatistical model