Benchmarking computational decontamination of ambient RNA
Cecilie B Cargnelli, Jakob Vennike Nielsen, Jesper Grud Skat Madsen
This study benchmarks ambient RNA decontamination methods using simulated and experimental datasets, finding that no single method is optimal across all scenarios, with CellBender, DecontX, and SoupX performing well.
Frontiers in Bioinformatics · Aug 19, 2026Peer-reviewedBioinformatics