Li Zheng

A lenvatinib-resistance-derived transcriptional program identifies metabolic identity remodeling associated with unfavorable survival in hepatocellular carcinoma

This paper identifies a transcriptional program from lenvatinib-resistant HCC cells that correlates with poor survival in an independent patient cohort, highlighting metabolic identity remodeling.

Spatial vascular/BTB remodeling and malignant-state plasticity in glioblastoma

This study identifies spatially distinct vascular and BTB remodeling programs in glioblastoma and explores malignant-state plasticity across tumor compartments.