ImmunologyFrontiers in ImmunologyPeer-reviewed
Comprehensive analysis of αβT-cell receptor repertoires reveals signatures of thymic selection
Daniil V. Luppov, Elizaveta K. Vlasova, Dmitriy M. Chudakov, Mikhail Shugay
This study analyzes T-cell receptor repertoires to identify how thymic selection shapes TCR diversity and lineage commitment through changes in CDR3 properties and MHC haplotype effects.