PINK1 loss in astrocytes triggers inflammatory dysfunction and neuronal death
Gabriella Fiorino, Damian Nicolas Di Florio, Deshaun H Hadley, Owen A. Ross, Fabienne C. Fiesel, Wolfdieter Springer
This study shows that PINK1 loss in astrocytes causes inflammation and neuronal death through non-cell-autonomous mechanisms, and that autophagy enhancement can reverse these effects.
bioRxiv · Jun 9, 2026 · PreprintNeuroscience