Explainable Generative AI Uncovers a Molecular Continuum in Medulloblastoma with Implications for Rare Cancer Subtyping and Treatment Equity
Guillermo Prol-Castelo, Alejandro Tejada-Lapuerta, Beatriz Urda-García, Iker Núñez‐Carpintero, Erica Garcia-Verellen, Arnau Montagud, Alfonso Valencia, Davide Cirillo
This study uses synthetic data generation and explainable AI to uncover an intermediate subgroup in medulloblastoma, highlighting treatment disparities and supporting the continuum hypothesis between Groups 3 and 4.
bioRxiv · Dec 30, 2024 · PreprintBioinformatics