Author

Pik Ki Lau

University of California San DiegoORCID 0009-0005-4405-9746Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:Hi-C· 3 Organism:human· 3 Assay:ATAC-seq· 2 Assay:DNA methylation· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

Bing ReniD· 3 shared Keyi DongiD· 3 shared Nathan R. ZemkeiD· 3 shared Weronika M. BartosikiD· 3 shared Chanrung SengiD· 2 shared Daofeng LiiD· 2 shared Joseph R. EckeriD· 2 shared Seo Yeon LeeiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersGenomics

Bing RenORCID

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3 papers

Recent·Most cited

GenomicsScience AdvancesPeer-reviewedJul 23, 2026

Single-cell analysis of the epigenome and 3D chromatin architecture in the human retina

Ying Yuan, Pooja Biswas, Nathan R. Zemke…·Bing Ren

The paper performs single-cell multiomics analysis of the human retina to identify regulatory elements and develop predictors for non-coding risk variants.

6 citations

humanscRNA-seq

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GenomicsSciencePeer-reviewedJul 23, 2026

Epigenetic and 3D genome reprogramming during the aging of human hippocampus

Nathan R. Zemke, Seo Yeon Lee, Sainath Mamde…·Bing Ren

This study examines age-related changes in the human hippocampus using multi-omics data, revealing cell-type loss and epigenetic reprogramming linked to cognitive decline.

18 citationstop 1%

humanscRNA-seq

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GenomicsbioRxivPreprintJan 9, 2025

Dose-dependent sensitivity of human 3D chromatin to a heart disease-linked transcription factor

Zoe L. Grant, Shuzhen Kuang, Shu Zhang…·Benoit G. Bruneau

This study shows that reduced TBX5 dosage affects 3D chromatin organization in human cardiomyocytes, with cell-to-cell variation and partial protection by CTCF co-occupancy.

13 citations

humanChIP-seq

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