Author

Dave Burke

Arc Research InstituteORCID 0009-0006-3058-4184Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Assay:perturbation screen· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Abhinav AdduriiD· 1 shared Basak EraslaniD· 1 shared Beatrice BevilacquaiD· 1 shared Hani GoodarziiD· 1 shared Rishi VermaiD· 1 shared Yusuf RoohaniiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBioinformatics

Abhinav AdduriORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintOct 5, 2026

✦ In-depth digest

PIE: Generalizing perturbation effects across unseen perturbations, contexts and datasets

Rishi Verma, Abhinav Adduri, Beatrice Bevilacqua…·Yusuf Roohani

Predicting differentially expressed genes and expression shifts per condition from database embeddings plus per-gene evidence, PIE reaches 1.2–3.2 times the best baseline's AUPRC on unseen contexts, perturbations and datasets.

1 citation

humanscRNA-seq

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