BioinformaticsbioRxivPreprint
Prefrontal cortex transcriptomes distinguish Alzheimers disease from asymptomatic amyloid pathology, neuropeptide loss, immune-complement activation and glial remodelling
Yusuf Aliyu Munir, Umar Sagir, Fahad Sajjad…·Ibrahim Maikudi Sani
This study identifies distinct transcriptional signatures in the prefrontal cortex of Alzheimer's disease patients compared to asymptomatic amyloid pathology and controls, highlighting neuropeptide loss, immune activation, and glial remodeling.
DOI 10.64898/2026.10.31.763276