IEEE Transactions on Medical ImagingNeurosciencePeer-reviewed journal article
Higher order spherical harmonics reconstruction of fetal diffusion MRI with intensity correction
Maria DepreziD, Anthony N. PriceiD, Daan ChristiaensiD, Georgia Lockwood EstriniD, Lucilio Cordero‐GrandeiD, Jana Maria HutteriD, Alessandro DaducciiD, Jacques‐Donald TournieriD, Mary RutherfordiD, Serena Jane CounselliD, Meritxell Bach CuadraiD, Joseph V. HajnaliD
Abstract
We present a comprehensive method for reconstruction of fetal diffusion MRI signal using a higher order spherical harmonics representation, that includes motion, distortion and intensity correction. By applying constrained spherical deconvolution and whole brain tractography to reconstructed fetal diffusion MRI we are able to identify main WM tracts and anatomically plausible fiber crossings. The proposed methodology facilitates detailed investigation of developing brain connectivity and microstructure in-utero.
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