Simon Keith Warfield

Insights into Temporal and Spatial Dynamics of Short Association Fiber Formation in the Human Fetal Brain

This study reconstructs the development of short association fibers in the human fetal brain using diffusion MRI and histology validation, revealing their maturation patterns and implications for neurodevelopmental disorders.

Charting the Normal Development of Structural Brain Connectivity in Utero using Diffusion MRI

This study maps fetal brain structural connectivity using diffusion MRI, revealing developmental patterns and introducing a new method for creating age-specific connectome templates.

Detailed delineation of the fetal brain in diffusion MRI via multi-task learning

This paper develops a multi-task deep learning method to segment and parcellate fetal brain structures from diffusion MRI, achieving high accuracy in tissue segmentation, tract segmentation, and parcellation.

White matter tract crossing and bottleneck regions in the fetal brain

This study quantifies crossing tracts and bottleneck regions in fetal brain white matter using diffusion MRI, finding high prevalence of both features compared to adult brains.

A detailed spatio-temporal atlas of the white matter tracts for the fetal brain

This study constructs a spatiotemporal atlas of fetal white matter tracts using dMRI, revealing developmental patterns of FA and MD across gestational weeks 22-37.

Large deletions perturb peripheral transcriptomic and metabolomic profiles in Phelan-McDermid syndrome

This study identifies molecular differences between PMS patients with small and large deletions, showing reduced cytotoxic cell signatures and sphingolipid metabolism in large deletions.

Heterogeneous migration of neuronal progenitors to the insula shapes the human brain

The paper shows that the insula develops through curved migration of progenitor cells due to obstruction by lenticular nuclei, challenging existing radial migration models.

Objective Evaluation of Multiple Sclerosis Lesion Segmentation using a Data Management and Processing Infrastructure

This paper evaluates MS lesion segmentation algorithms using a new open-science infrastructure, finding that automatic methods lag behind human experts in detection and delineation.

A three year follow-up study of gadolinium enhanced and non-enhanced regions in multiple sclerosis lesions using a multi-compartment T2 relaxometry model

This study uses a multi-compartment T2 relaxometry model to analyze changes in water fractions in MS lesions over three years, finding significant differences between gadolinium-enhanced and non-enhanced regions.

Presurgical language fMRI: Current technical practices in epilepsy surgical planning

This study surveys current practices in presurgical language fMRI for epilepsy, finding significant variability in protocols, tasks, analysis methods, and expertise involvement.

Presurgical language fMRI: Current practices and patient outcomes in epilepsy surgical planning

This study surveys global epilepsy surgical programs on their use of presurgical language fMRI and reports mixed outcomes in localizing language cortex and predicting post-surgical function.