Heritability of hierarchical structural brain network
Moo Kwon ChungiD, Zhan LuoiD, Nagesh AdluruiD, Andrew L. AlexanderiD, Davidson J. Richard, H. Hill GoldsmithiD
Abstract
We present a new structural brain network parcellation scheme that can subdivide existing parcellations into smaller subregions in a hierarchically nested fashion. The hierarchical parcellation was used to build multilayer convolutional structural brain networks that preserve topology across different network scales. As an application, we applied the method to diffusion weighted imaging study of 111 twin pairs. The genetic contribution of the whole brain structural connectivity was determined. We showed that the overall heritability is consistent across different network scales.
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