bioRxivBioengineeringPreprint
Adaptive Multimodal Temporal Transformer for Bio Signal Driven Stroke Rehabilitation Prognosis
Abstract
Stroke rehabilitation requires continuous, individualized assessment of recovery progress to optimize treatment planning. Existing prognosis models often rely on static, single-timepoint predictions and lack adaptive fusion of multi-modal bio-signals, limiting their clinical interpretability and utility. To address these challenges, we propose AMTT-Net, an adaptive multimodal temporal transformer for dynamic stroke rehabilitation prognosis. AMTT-Net integrates wearable biosensor data, video keypoints, and clinical records through an attention-based Adaptive Fusion Module and Trajectory-Aware Prediction Heads to jointly predict continuous recovery trajectories and responder likelihoods under different rehabilitation modalities. Evaluations on the StrokeBalance-Sim dataset demonstrate that AMTT-Net achieves superior performance in both trajectory regression and responder classification tasks, while providing interpretable, patient-specific insights to support personalized rehabilitation strategies.
- organism: human
- assay: imaging
- assay: clinical cohort / trial
- research focus: drug response / drug discovery
- approach: deep learning
- approach: transformer / foundation model
- Citations
- 1
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- Continuous lesion images drive more accurate predictions of outcomes after stroke than binary lesion images
Thomas M.H. Hope, Douglas Neville, … Cathy J. Price·bioRxiv·Oct 4, 2024
- Automated movement assessment in stroke rehabilitation
Tamim Ahmed, Kowshik Thopalli, … Steven L. Wolf·Frontiers in NeurologyPeer-reviewed·Aug 19, 2021
- Brain Stroke Prediction: A PSO Optimized Stacked Ensemble Machine Learning Approach with SMOTEEN Data Balancing
Achin Jain, Arun Kumar Dubey, … Saurav Mallik·bioRxiv·Jun 5, 2025
- A global effort to benchmark predictive models and reveal mechanistic diversity in long-term stroke outcomes
Anna Matsulevits, Pedro Alvez, … Michel Thiebaut de Schotten·bioRxiv·Oct 17, 2024
- Electrophysiological Signature of Stroke Recovery: Investigating EEG Biomarkers for Prognostic Insights
Majid Khalili‐Ardali, Vivek Sharma, … Nick F. Ramsey·Frontiers in StrokePeer-reviewed·Sep 28, 2026
- Data-driven biomarkers outperform theory-based biomarkers in predicting stroke motor outcomes
Emily R. Olafson, Christoph Sperber, … Amy F. Kuceyeski·bioRxiv·Jun 19, 2023