BioinformaticsBioinformaticsPeer-reviewed journal article
Predicting the subcellular location of prokaryotic proteins with DeepLocPro
Jaime MorenoiD, Henrik NielseniD, Ole WintheriD, Felix TeufeliD
Abstract
Protein subcellular location prediction is a widely explored task in bioinformatics because of its importance in proteomics research. We propose DeepLocPro, an extension to the popular method DeepLoc, tailored specifically to archaeal and bacterial organisms. DeepLocPro is a multiclass subcellular location prediction tool for prokaryotic proteins, trained on experimentally verified data curated from UniProt and PSORTdb. DeepLocPro compares favorably to the PSORTb 3.0 ensemble method, surpassing its performance across multiple metrics on our benchmark experiment. The DeepLocPro prediction tool is available online at https://ku.biolib.com/deeplocpro and https://services.healthtech.dtu.dk/services/DeepLocPro-1.0/.
- organism: bacteria (other)
- assay: proteomics
- research focus: protein structure prediction
- approach: deep learning
- Citations
- 76
- FWCI
- 10.32
- Field percentile
- top 1%
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- Protein Language Model for Prediction of Subcellular Localization of Protein Sequences from Gram-negative bacteria (ProtLM.SCL)
Gurpreet Singh, Ravi Tyagi, … Ahmed Essaghir·bioRxiv·Dec 16, 2022
- Prediction of protein subcellular localization using deep learning and data augmentation
Majid Ghorbani-Eftekhar·bioRxiv·May 19, 2020
- ProtFinder: finding subcellular locations of proteins using protein interaction networks
Aayush Grover, Laurent Gatto·bioRxiv·Jan 11, 2022
- PSL-Recommender: Protein Subcellular Localization Prediction using Recommender System
Ruhollah Jamali, Changiz Eslahchi, Soheil Jahangiri·bioRxiv·Apr 21, 2019
- Deep generative model for protein subcellular localization prediction
Guo-Hua Yuan, Jinzhe Li, … Li Yang·Briefings in BioinformaticsPeer-reviewed·Mar 1, 2025
- Predicting protein subcellular location using learned distributed representations from a protein-protein network
Xiaoyong Pan, Lei Chen, … Yu‐Dong Cai·bioRxiv·Sep 15, 2019