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Philosophical Transactions of the Royal Society B Biological SciencesBioinformaticsPeer-reviewed journal article

CardioVinci: building blocks for virtual cardiac cells using deep learning

Afshin KhadangiiD, Thomas BoudieriD, Eric G. HansseniD, Vijay RajagopaliD

PDFDOIPreprint

Abstract

Recent advances in high-throughput microscopy imaging have made it easier to acquire large volumes of cell images. Thanks to electron microscopy (EM) imaging, they provide a high-resolution and sufficient field of view that suits imaging large cell types, including cardiomyocytes. A significant bottleneck with these large datasets is the time taken to collect, extract and statistically analyse 3D changes in cardiac ultrastructures. We address this bottleneck with CardioVinci.

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