bioRxivBioinformaticsPreprint
Aligning sequence from molecular inversion probes
Brent S. Pedersen, Elissa Murphy, Ivana V. YangiD, David A. SchwartziD
Abstract
Summary: Molecular inversion probes (MIPs) allow efficient enrichment of genomic regions of interest for the purpose of targeted sequencing. To date, there is a paucity of simple-to-use software to align sequences derived from this method. Here, we describe a single program that performs mapping, arm removal, and deduplication before outputting alignments in SAM format. Availability: bwa-mips is available at https://github.com/brentp/bwa-mips under the MIT license. Contact: bpederse@gmail.com
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