Color tuning of neurons in face patches of macaque inferior temporal cortex

Abstract

Previous work has shown that under viewing conditions that break retinal mechanisms for color, one class of objects appears paradoxically colored: faces, and they look green. Interpreted within a Bayesian-observer framework, this observation makes the surprising prediction that face-selective neurons are sensitive to color and weakly biased for colors that elicit L>M cone activity (warm colors). We tested this hypothesis by measuring color-tuning responses of face-selective cells in alert macaque monkey, using fMRI-guided microelectrode recording of the middle and anterior face patches and carefully color-calibrated stimuli. The population of face-selective neurons showed significant color tuning when assessed using images that preserved the luminance contrast relationships of the original face photographs. A Fourier analysis of the color-tuning responses uncovered two components. The first harmonic was biased towards the L>M colors, consistent with the prediction. Interestingly, the second harmonic aligned with the S-cone cardinal axis, which may relate to the computation of animacy by IT cells. SignificanceThe results provide the first quantitative measurements of the color tuning properties of face-selective neurons. The results provide insight into the neural mechanisms that could support the role of color in face perception.