Cross-task implications: How hippocampal event boundary responses predict unrelated memory performance

Hippocampal responses at event boundaries have been shown to predict memory performance for these events. However, are these hippocampal event boundary responses specific to memory for those particular events, or can they also have predictive power across various memory tasks? We used data from the Cam-CAN project (fMRI data from continuous movie viewing and memory results from an unrelated Famous Faces Task, N = 630) to determine whether hippocampal responses at event boundaries during the continuous movie viewing were indicative of memory performance in the unrelated Famous Faces task using various machine learning algorithms. The results showed that memory performance in the Famous Faces Task could be predicted based on participants hippocampal event boundary responses in another task, which suggests that the hippocampal event boundary responses are indicative for general memory performance. This might indicate importance of these hippocampal event boundary responses in terms of general information processing of the human brain.