bioRxivMicrobiology
Haemophilus to meningococci transfer of beta-lactamase
Abstract
We report the detection in France of a beta-lactamase producing invasive meningococcal isolate. Whole genome sequencing of the isolate revealed ROB-1 type beta-lactamase that is frequently encountered in Haemophilus influenzae suggesting horizontal transfer between isolates of these bacterial species. Beta-lactamases are exceptional in meningococci with no reports from more than two decades. This report is worrying as the expansion of such isolates may jeopardize the effective treatment against invasive meningococcal disease.
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- Inter-phylum circulation of a beta-lactamase - encoding gene: a rare but observable event
R. GSCHWIND, M. Petitjean, … E. RUPPE·bioRxiv·Nov 10, 2023
- Are new beta-lactamases posing a potential future threat?
Patrik Mlynárčik, Veronika Zdarska, Milan Kolář·AntibioticsPeer-reviewed·Nov 20, 2025
- Biochemical characterization of extended-spectrum β-lactamases from Akkermansia genus
Jiafu Lin, Tiantian Wang, … Tao Song·bioRxiv·Jun 10, 2024
- First report and characterization of a plasmid-encoded blaSFO-1 in a multi-drug resistant Aeromonas hydrophila clinical isolate
T. Skwor, D. C. Jones, … R. J. Newton·bioRxiv·Feb 1, 2024
- Genomic insights into six clinical isolates of Stenotrophomonas maltophilia from Northern India
Nazneen Gheewalla, Yuvraj Jadhav, … Shraddha Madhav Karve·bioRxiv·Jan 13, 2025
- Impact of different amino acid substitutions in penicillin-binding protein 3 on beta-lactam susceptibility in Haemophilus influenzae