Philosophy and History of Science

Information-theoretic Limits on Programmatic Specification of Biological Systems

The paper uses information theory to show that biological organization cannot be fully specified by an organism's own program, but instead arises from a coarse-grained specification by a shared physical background.

Particle Biology: A Perspective on a First-Principles Theory of Life

This paper proposes Particle Biology as a theoretical framework to unify life science research by focusing on electromagnetic interactions at the atomic level.

Constraint Semantics for Multi-level Organization

The paper introduces a constraint-based semantic framework to model multi-level biological organisation, demonstrating its application to excitable-cell dynamics.

A Priori recognition for biological phenomena prior to empirical understanding

This study introduces BECC, a framework for categorizing cellular behaviors into 11 types, validated through STAT3 phosphorylation and T cell differentiation, to improve open and reproducible science.