Lactucopicrin: A sesquiterpene lactone with anti-inflammatory activity modulates the crosstalk between NF-kB and AHR pathways
María Ángeles Ávila‐Gálvez, Catarina J G Pinto, Carlos Rafael-Pita, Inês P. Silva, Aleksandra T. Janowska, Sérgio Pires Marinho, Rory Saitch, Yilong Lian, Pakavarin Louphrasitthiphol, Jonas Protze, Gerd Krause, Pedro Moura‐Alves, Cláudia Nunes dos Santos
This study identifies lactucopicrin, a sesquiterpene lactone from chicory, as a dual modulator of NF-kB and AHR pathways with anti-inflammatory effects.
Journal of Medicinal Chemistry · Nov 4, 2025Peer-reviewedMolecular Biology