Ion-surface interactions and analysis

Molecular biointerface characterisation for an implanted medical device using cryogenic orbitrap secondary ion mass spectrometry (Cryo-OrbiSIMS)

This paper uses Cryo-OrbiSIMS to analyze metabolomics at the biointerface of implanted catheters, identifying early and late-stage biomolecular responses in mice.

Subcellular localization of drug distribution by super-resolution ion beam imaging

The paper introduces srIBI, a super-resolution imaging technique, to visualize subcellular localization of biomolecules and drugs at the nanometer scale.

Ion beam subcellular tomography

This paper introduces ion beam tomography (IBT), a 3D subcellular imaging technique, and demonstrates its ability to visualize genomic regions, RNA transcripts, and protein factors with high resolution.