Oxidative Stress and Tissue Remodeling in a Rat Abdominal Seroma Model
Xiaochao Xia, Ann M. Nour, Kevin He, Adam Boukind, Yuhan Guo, Sida Hao, Batool Arif, Lauren Schellhardt, Mohamed Adel Zayed, Andrew E. Gelman, Matthew D. Wood, Justin Michael Sacks, Li Xiaowei
This study develops a rat abdominal seroma model and shows that seroma fluid resolution does not align with stromal recovery, highlighting persistent oxidative stress, inflammation, fibrosis, and vascular remodeling.
bioRxiv · Oct 7, 2026 · PreprintBioengineering