Vaccination of pregnant mares with mRNA encoding a GPI-anchored form of the virulence-associated protein A of Rhodococcus equi induces strong IgG responses that are transferred to their foals
Cohen Noah, Nathan M. Canaday, A. S. de Oliveira, Shelby Z. Wehmeyer, Cassidi N. Velez, Macy J. Fox, Maria T. Sanabria, M.H. Jesie Frisbie, Kerstin K. Landrock, Karin E. R. Borba, Ashley L. Jenkins, Angela Ilha Bordin, Jeroen B. K. Pollet
This study shows that vaccinating pregnant mares with mRNA encoding GPI-anchored VapA of R. equi leads to transfer of VapA-specific IgG to foals, providing passive immunity.
bioRxiv · Oct 29, 2026 · PreprintImmunology