Topic · Complementary and alternative medicine · Medicine

Andrographolide Research and Applications

OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.

2 papers

Immuno-Impaired Expression of Synaptophysin, GFAP and Nissl Substances in the Cerebral Cortex of Diabetic Wistar Rats; Evaluation of Andrographis Paniculata Effects

Ismail Olasile Onanuga, Royhaan Olamide Folarin, Elijah Taiwo MUNIRU, Ridwan Babatunde IBRAHIM, Ibe Michael Usman, Ayoola Isaac Jegede, Onyemaechi Okpara Azu, Temidire Odunayo OBAYA, M.O. Kehinde

This study evaluates the neuroprotective effects of Andrographis paniculata on diabetic Wistar rats, showing improved cerebral morphology and reduced astrocyte activation when combined with metformin.

Biology Medicine & Natural Product Chemistry · May 8, 2026Peer-reviewedPharmacology & Toxicology

Andrographolide prevents necroptosis by suppressing generation of reactive oxygen species

Na Lu, Qing Li, Linghan Duan, Rong Xu, Yaping Li, Fuli Shi, Zhi-ya Zhou, Ying-qing Gan, Bo Hu, Jinhua Li, Xian‐Hui He, Dong‐Yun Ouyang, Qingbing Zha

This study shows that Andrographolide inhibits necroptosis by reducing ROS and activating Nrf2, while its derivatives do not exhibit similar effects.

Acta Biochimica et Biophysica Sinica · May 8, 2025Peer-reviewedPharmacology & Toxicology