Topic · Surgery · Medicine

Hydrogen's biological and therapeutic effects

OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.

2 papers

Evaluating the Safety of Intravenous Injection of Nitric Oxide, Magnesium, and Hydrogen Nano Bubble Solution in Sprague Dawley Rats

Dody Novrial, Nor Sri Inayati, Nur Signa Aini Gumilas, Dhadhang Wahyu Kurniawan, Sutiman Bambang Sumitro

The study evaluates the safety of intravenous HNB solution with NO and magnesium in rats, finding no adverse effects but noting the need for long-term studies.

bioRxiv · Jun 16, 2025 · PreprintPharmacology & Toxicology

Hydrogen-Induced Calcium Influx via the TRPC4-TRPC4AP Axis

Pengxiang Zhao, Han Li, Zisong Cai, Xujuan Zhang, Xiaohu Wen, Ziyi Liu, Shibo Jiang, Zheng Dang, Xue Dong Jiang, Jiateng Wang, Mengyu Liu, Fei Xie, Xuemei Ma

This study identifies molecular hydrogen as a novel calcium agonist that activates the TRPC4-TRPC4AP axis to regulate extracellular calcium influx, with implications for therapeutic applications in calcium-related disorders.

bioRxiv · Mar 19, 2025 · PreprintBiochemistry