Hyper-proliferation of Adipose Progenitors During Developmental Adipogenesis Programs Higher Adipocyte Number and Early-onset Obesity in Offspring Born to Obese Dams
Taylor B. Scheidl, Ji Soo Yoon, Jessica L. Wager, Sophie Z. Yonan, A Lakhdar, Senthilkumar Kailasam, JA Thompson
The paper identifies hyper-proliferation of adipose progenitors in offspring of obese mothers as a mechanism for early-onset obesity and increased adipocyte number.
bioRxiv · Sep 13, 2025 · PreprintDevelopmental Biology