Phloiokeratosis - a new ichthyosiform hyperkeratotic cornification disorder in dogs with SUV39H1 variants
Sarah Kiener, Stefan J. Rietmann, Sara Soto, Sara J. Ramos, Cherie M. Pucheu‐Haston, Chi‐Yen Wu, Desirae Wheatcraft, A Simpson, Susanne Åhman, Brett E. Wildermuth, Michaela Drögemüller, Vidhya Jagannathan, Charles W. Bradley, Elizabeth A. Mauldin, Nadine M. Meertens, , Tosso Leeb
This study identifies SUV39H1 variants in dogs with a new skin disorder, linking SUV39H1 deficiency to epidermal hyperkeratosis and highlighting its role in keratinocyte differentiation.
Scientific Reports · Jun 25, 2026Peer-reviewedGenetics