Author

Sara Soto

University of BernORCID 0000-0003-3777-8724Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

A Simpson· 1 shared Andrew H. SongiD· 1 shared Andrew ZhangiD· 1 shared Brett E. Wildermuth· 1 shared Charles W. BradleyiD· 1 shared Cherie M. Pucheu‐HastoniD· 1 shared Chi‐Yen WuiD· 1 shared Christine GoepfertiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

A Simpson

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2 papers

Recent·Most cited

GeneticsScientific ReportsPeer-reviewedJun 25, 2026

Phloiokeratosis - a new ichthyosiform hyperkeratotic cornification disorder in dogs with SUV39H1 variants

Sarah Kiener, Stefan J. Rietmann, Sara Soto…·Tosso Leeb

This study identifies SUV39H1 variants in dogs with a new skin disorder, linking SUV39H1 deficiency to epidermal hyperkeratosis and highlighting its role in keratinocyte differentiation.

DOI 10.1038/s41598-026-59288-y

statistical modelgene regulatory network inference

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BioinformaticsbioRxivPreprintJul 20, 2024

Deep Learning-based Modeling for Preclinical Drug Safety Assessment

Guillaume Jaume, Simone de Brot, Andrew H. Song…·Faisal Mahmood

This paper introduces TRACE, a deep learning model for automated liver histopathology assessment in preclinical drug safety, achieving higher concordance than pathologists in lesion scoring and dose-response analysis.

5 citations

ratimaging

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