Delayed puberty, gonadotropin abnormalities and subfertility in male Padi2/Padi4 double knockout mice
Kelly L. Sams, Chinatsu Mukai, Brooke A. Marks, Chitvan Mittal, Elena A. Demeter, Sophie R. Nelissen, Jennifer K. Grenier, A Tate, Faraz Ahmed, Scott Alexander Coonrod
This study shows that male Padi2/Padi4 double knockout mice exhibit delayed puberty, reduced fertility, and lower testosterone levels, linking PADs to hormone signaling in vivo.
Reproductive Biology and Endocrinology · Oct 12, 2022Peer-reviewedMolecular Biology