Implementation of Design of Experiments (DOE) for Optimization of Feeding Strategy and Glyco-Engineering of Trastuzumab Biosimilar
R. Mahboudi, S. Samavat, A. Afrah, M. Khorshidtalab, A. Fadaei Tehran, P. Motahari, F. Jafari, S. Maleknia
This study optimizes feeding strategies and glyco-engineering of trastuzumab biosimilar using design of experiments, improving galactosylation and afucosylation while maintaining product quality.
bioRxiv · Mar 21, 2019 · PreprintBioengineering