Methylome-dependent transformation of emm1 group A streptococci
J. Alves, J. D. Rand, A. B. Johnston, C. Bowen, N. N. Lynskey
This paper identifies a methylome-dependent restriction barrier in emm1 group A streptococci that limits transformation and presents an improved protocol using phage anti-restriction protein Ocr to overcome this barrier.
bioRxiv · Apr 10, 2023 · PreprintMicrobiology